Anti-diabetic Properties of Moringa Oleifera

Anti-diabetic Properties of Moringa Oleifera

Quote from ”A Review on the Anti-diabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets”

According to the World Health Organization, diabetes mellitus is amongst the top ten leading causes of mortality and morbidity around the world (World Health Organization, 2022). Diabetes is a metabolic disorder that is characterized by a state of hyperglycemia, that occurs alongside dysregulations in insulin levels and in some cases, it arises concurrently to overweight and obesity (International Diabetes Federation, 2021). Indeed, excessive body fat or obesity remains the major culprits in the development of type 2 diabetes (T2D), which is the predominant form of diabetes (International Diabetes Federation, 2021).

Accumulative research shows that Moringa oleifera exhibits a lot of important biological properties such as antioxidant, anti-inflammation, anti-hyperglycemic properties over the past years proving that it is a good plant to use as an alternative therapeutic for diabetes (Omodanisi et al., 2017b; Gothai et al., 2017; Paula et al., 2017; Abd et al., 2020; Xiong et al., 2021).

The leaves are utilized the most for medicinal purposes and they are a great source of prominent anti-inflammatory and antioxidant flavonoids, namely myricetin, quercetin and kaempferol (Vergara-Jimenez et al., 2017). Interesting, these bioactive compounds are known to contain potential anticancer, hypolipidemic, hypotensive and antidiabetic properties, antioxidant and anti-inflammatory (Vergara-Jimenez et al., 2017). Other documented uses for this medicinal plant include its application as a diuretic, a testosterone stimulant, an antifungal and as an antibacterial (Mishra et al., 2011; Kumar et al., 2018). It can also be used to relieve a sore throat and symptoms of influenza, or as an anti-inflammatory agent (Mishra et al., 2011). Interestingly, evidence has grown that Moringa oleifera contains hypoglycemic effects in diabetic animal models, including its associated complications such as oxidative stress and inflammation (Balakrishnan et al., 2019; Chin et al., 2019; Bao et al., 2020).

Source: 
Fikile T. MthiyaneFikile T. Mthiyane, A Review on the Antidiabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets, Front. Pharmacol. , 11 July 2022